ChromoQuant® Optima XY is a single tube QF-PCR kit for analysing aneuploidy in chromosomes X and Y, including Klinefelter and Turner X0 syndroms.
The test can be used for verification of uninformative results with previous tests or for verification and diagnosis of positive indications from NIPT screening.
· Single tube test – all markers analysed in one PCR reaction.
· 13 markers in total for Chr. X and Y
· Taq polymerase included, ready to use
· The diagnostic procedure is based upon amniocentesis if used for prenatal diagnosis. Results are achieved within 6 hours enabling a "time to reply" of less than 24 hours
· The test can be used in combination with the ChromoQuant AZF kit in order to diagnose Klinefelter syndrome.
· The test has been clinically validated for In Vitro Diagnostics and is CE marked
· The ChromoQuant® kit is validated for ABI sequencers
· Data evaluation is facilitated by the proprietary ChromoQuant® Visualizer™ decision support software, licensed to all users
· Templates and panels for ABI´s GeneMapper and SoftGenetics´ GeneMarker are available for
download.
· Detection of maternal contamination eliminate risk of misdiagnosis
ChromoQuant® is CE marked for IVD use and produced according to ISO13485
For more information download product sheet
or contact
sales@cybergene.se
Product information
Intended Use |
In vitro diagnostics for diagnosis of aneuploidy in chromosomes 13, 18, 21 and X/Y |
Product no. |
514.604-26 |
No. of markers |
Single tube PCR containing 13 markers |
| |
Chromosome X: 6 markers ChromosomeY: 2 markers Chromosome X and Y: 4 markers Turner X0 verifying TAF9B: 1 marker |
| DNA source |
Blood, saliva, mouth swab, amniotic fluid, CVS |
| Taq polymerase included |
Yes |
| No. of reactions per patient |
1 |
| CE-labelled for IVD use |
Yes |
| Detection format |
Capillary electrophoresis |
Validated Genetic Analysers |
ABI310, 3100, 3130, 3730, 3500 |
| Data Interpretation |
GeneMapper and GeneMarker templates and panels are available. Visualizer decision support software free of charge |
